Anti-RTP4 antibody (189-239 aa) (STJ195698)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human RTP4 at the amino acid range 189-239
General Information
| Short Description | Rabbit polyclonal anti-Receptor-transporting protein 4 (189-239 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RTP4 |
| Gene ID | 64108 |
| Uniprot ID | RTP4_HUMAN |
| Immunogen | Synthesized peptide derived from the human RTP4 at the amino acid range 189-239 |
| Immunogen Region | 189-239 aa |
| Specificity | This antibody detects endogenous levels of RTP4 at Human/Mouse |
Additional Info
| Function | Chaperone protein that facilitates the trafficking and functional cell surface expression of some G-protein coupled receptors (GPCRs). Promotes functional expression of the bitter taste receptor TAS2R16. Also promotes functional expression of the opioid receptor heterodimer OPRD1-OPRM1. In addition, acts as a potent IFN-inducible suppressor of pathogens including lyssavirus rabies, influenza A or yellow fever virus. Mechanistically, associates with the viral replicase, binds viral RNA, and thereby suppresses viral genome amplification that replicates at the endoplasmic reticulum. In addition, restores antiviral signaling by interacting with and sequestering influenza A virus protein NS1. |
| Protein Name | Receptor-Transporting Protein 428 Kda Interferon-Responsive Protein3cxxc-Type Zinc Finger Protein 4 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type Iii Membrane ProteinCytoplasm |
| Alternative Antibody Names | Anti-Receptor-Transporting Protein 4 antibodyAnti-28 Kda Interferon-Responsive Protein antibodyAnti-3cxxc-Type Zinc Finger Protein 4 antibodyAnti-RTP4 antibodyAnti-IFRG28 antibodyAnti-Z3CXXC4 antibody |
Information sourced from Uniprot.org