| Function | Chaperone protein that facilitates the trafficking and functional cell surface expression of some G-protein coupled receptors (GPCRs). Promotes functional expression of the bitter taste receptor TAS2R16. Also promotes functional expression of the opioid receptor heterodimer OPRD1-OPRM1. In addition, acts as a potent IFN-inducible suppressor of pathogens including lyssavirus rabies, influenza A or yellow fever virus. Mechanistically, associates with the viral replicase, binds viral RNA, and thereby suppresses viral genome amplification that replicates at the endoplasmic reticulum. In addition, restores antiviral signaling by interacting with and sequestering influenza A virus protein NS1. |
| Protein Name | Receptor-Transporting Protein 428 Kda Interferon-Responsive Protein3cxxc-Type Zinc Finger Protein 4 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type Iii Membrane ProteinCytoplasm |
| Alternative Antibody Names | Anti-Receptor-Transporting Protein 4 antibodyAnti-28 Kda Interferon-Responsive Protein antibodyAnti-3cxxc-Type Zinc Finger Protein 4 antibodyAnti-RTP4 antibodyAnti-IFRG28 antibodyAnti-Z3CXXC4 antibody |
Information sourced from Uniprot.org
