| Short Description : | Rabbit polyclonal RRM1 (593-792) antibody for use in WB, IHC-P, IF, ICC, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IF/ICC/IP/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specif |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RRM1 |
| Gene ID: | 6240 |
| Uniprot ID: | RIR1_HUMAN |
| Immunogen Region: | 593-792 |
| Immunogen Sequence: | IRNSLLIAPMPTASTAQILG NNESIEPYTSNIYTRRVLSG EFQIVNPHLLKDLTERGLWH EEMKNQIIACNGSIQSIPEI PDDLKQLYKTVWEISQKTVL KMAAERGAFIDQSQSLNIHI AEPNYGKLTSMHFYGWKQGL KTGMYYLRTRPAANPIQFTL NKEKLKDKEKVSKEEEEKER NTAAMVCSLENRDECLMCGS |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 593-792 of human RRM1 (NP_001024.1). |
| Function | Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. |
| Protein Name | Ribonucleoside-Diphosphate Reductase Large SubunitRibonucleoside-Diphosphate Reductase Subunit M1Ribonucleotide Reductase Large Subunit |
| Database Links | Reactome: R-HSA-499943 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ribonucleoside-Diphosphate Reductase Large Subunit antibodyAnti-Ribonucleoside-Diphosphate Reductase Subunit M1 antibodyAnti-Ribonucleotide Reductase Large Subunit antibodyAnti-RRM1 antibodyAnti-RR1 antibody |
Information sourced from Uniprot.org
