| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Ribosomal protein S6 kinase alpha-6 (661-710 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RPS6KA6 |
| Gene ID: | 27330 |
| Uniprot ID: | KS6A6_HUMAN |
| Immunogen Region: | 661-710 aa |
| Specificity: | Rsk-4 Polyclonal Antibody detects endogenous levels of Rsk-4 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human S6K-alpha6 at the amino acid range 661-710 |
| Function | Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis. |
| Protein Name | Ribosomal Protein S6 Kinase Alpha-6S6k-Alpha-690 Kda Ribosomal Protein S6 Kinase 6P90-Rsk 6P90rsk6Ribosomal S6 Kinase 4Rsk-4Pp90rsk4 |
| Database Links | Reactome: R-HSA-437239Reactome: R-HSA-442742Reactome: R-HSA-444257 |
| Cellular Localisation | CytoplasmCytosolNucleusPredominantly Cytosolic |
| Alternative Antibody Names | Anti-Ribosomal Protein S6 Kinase Alpha-6 antibodyAnti-S6k-Alpha-6 antibodyAnti-90 Kda Ribosomal Protein S6 Kinase 6 antibodyAnti-P90-Rsk 6 antibodyAnti-P90rsk6 antibodyAnti-Ribosomal S6 Kinase 4 antibodyAnti-Rsk-4 antibodyAnti-Pp90rsk4 antibodyAnti-RPS6KA6 antibodyAnti-RSK4 antibody |
Information sourced from Uniprot.org