Anti-RPS19BP1 antibody (71-120 aa) (STJ95492)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human RPS19BP1 at the amino acid range 71-120
General Information
| Short Description | Rabbit polyclonal anti-Active regulator of SIRT1 (71-120 aa) for use in IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RPS19BP1 |
| Gene ID | 91582 |
| Uniprot ID | AROS_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human RPS19BP1 at the amino acid range 71-120 |
| Immunogen Region | 71-120 aa |
| Specificity | Ribosomal Protein S19BP Polyclonal Antibody detects endogenous levels of Ribosomal Protein S19BP protein. |
Additional Info
| Post Translational Modifications | Citrullinated by PADI4. |
| Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Acts as a chaperone that specifically mediates the integration of RPS19 in state post-A1. Direct regulator of SIRT1. Enhances SIRT1-mediated deacetylation of p53/TP53, thereby participating in inhibition of p53/TP53-mediated transcriptional activity. |
| Protein Name | Active Regulator Of Sirt140s Ribosomal Protein S19-Binding Protein 1Rps19-Binding Protein 1S19bp |
| Database Links | Reactome: R-HSA-3371453 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Active Regulator Of Sirt1 antibodyAnti-40s Ribosomal Protein S19-Binding Protein 1 antibodyAnti-Rps19-Binding Protein 1 antibodyAnti-S19bp antibodyAnti-RPS19BP1 antibodyAnti-AROS antibody |
Information sourced from Uniprot.org