| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RPL17 |
| Gene ID: | 6139 |
| Uniprot ID: | RL17_HUMAN |
| Immunogen Region: | 1-184 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-184 of human RPL17 (NP_000976.1). |
| Immunogen Sequence: | MVRYSLDPENPTKSCKSRGS NLRVHFKNTRETAQAIKGMH IRKATKYLKDVTLQKQCVPF RRYNGGVGRCAQAKQWGWTQ GRWPKKSAEFLLHMLKNAES NAELKGLDVDSLVIEHIQVN KAPKMRRRTYRAHGRINPYM SSPCHIEMILTEKEQIVPKP EEEVAQKKKISQKKLKKQKL MARE |
| Tissue Specificity | Expressed in pancreas, lung, colon, cystic duct, gall bladder, kidney and liver. Expressed at high levels in the well differentiated pancreatic tumor cell lines HPAF, COLO 357 and Capan-1, the moderately differentiated pancreatic tumor cell lines T3M-4, AsPc-1 and BxPc-3, the poorly differentiated pancreatic tumor cell line MIA PaCa-2, and the pancreatic tumor cell lines of undefined differentiation status such as SW979. Expressed at lower levels in the poorly differentiated pancreatic tumor cell lines HCG-25 and PANC-1. |
| Function | Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. |
| Protein Name | Large Ribosomal Subunit Protein Ul2260s Ribosomal Protein L1760s Ribosomal Protein L23Pd-1 |
| Database Links | Reactome: R-HSA-156827Reactome: R-HSA-156902Reactome: R-HSA-1799339Reactome: R-HSA-192823Reactome: R-HSA-2408557Reactome: R-HSA-6791226Reactome: R-HSA-72689Reactome: R-HSA-72706Reactome: R-HSA-72764Reactome: R-HSA-9010553Reactome: R-HSA-9633012Reactome: R-HSA-975956Reactome: R-HSA-975957 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Large Ribosomal Subunit Protein Ul22 antibodyAnti-60s Ribosomal Protein L17 antibodyAnti-60s Ribosomal Protein L23 antibodyAnti-Pd-1 antibodyAnti-RPL17 antibody |
Information sourced from Uniprot.org
