| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RPH3AL |
| Gene ID: | 9501 |
| Uniprot ID: | RPH3L_HUMAN |
| Immunogen Region: | 161-315 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 161-315 of human RPH3AL (NP_008918.1). |
| Immunogen Sequence: | KYILPLKTPGRADDPHFRPL PTEPAEREPRSSETSRIYTW ARGRVVSSDSDSDSDLSSSS LEDRLPSTGVRDRKGDKPWK ESGGSVEAPRMGFTHPPGHL SGCQSSLASGETGTGSADPP GGPRPGLTRRAPVKDTPGRA PAADAAPAGPSSCLG |
| Tissue Specificity | Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells. |
| Function | Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells. Acts as a potential RAB3B effector protein in epithelial cells. |
| Protein Name | Rab Effector Noc2No C2 Domains ProteinRabphilin-3a-Like Protein |
| Cellular Localisation | CytoplasmCytoplasmic VesicleSecretory Vesicle MembraneRecruited To The Vesicle Membrane In A Gtp- And Rab3b-Dependent Manner In Epithelial Cells |
| Alternative Antibody Names | Anti-Rab Effector Noc2 antibodyAnti-No C2 Domains Protein antibodyAnti-Rabphilin-3a-Like Protein antibodyAnti-RPH3AL antibodyAnti-NOC2 antibody |
Information sourced from Uniprot.org