Anti-RP1 antibody (250-500 aa) (STJ11106365)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RP1 (250-500 aa) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RP1 |
| Gene ID | 6101 |
| Uniprot ID | RP1_HUMAN |
| Immunogen Region | 250-500 aa |
| Immunogen Sequence | VYPKGNAKSESRKISTHMSS SSRSQIYSVSSEKTHNNDCY LDYSFVPEKYLALEKNDSQN LPIYPSEDDIEKSIIFNQDG TMTVEMKVRFRIKEEETIKW TTTVSKTGPSNNDEKSEMSF PGRTESRSSGLKLAACSFSA DVSPMERSSNQEGSLAEEIN IQMTDQVAETCSSASWENAT VDTDIIQGTQDQAKHRFYRP PTPGLRRVRQKKSVIGSVTL VSETEVQEKMIGQFSYSEE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 250-500 of human RP1 (NP_006260.1). |
Additional Info
| Tissue Specificity | Expressed in retina. Not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, spleen and pancreas. |
| Function | Microtubule-associated protein regulating the stability and length of the microtubule-based axoneme of photoreceptors. Required for the differentiation of photoreceptor cells, it plays a role in the organization of the outer segment of rod and cone photoreceptors ensuring the correct orientation and higher-order stacking of outer segment disks along the photoreceptor axoneme. |
| Protein Name | Oxygen-Regulated Protein 1Retinitis Pigmentosa 1 ProteinRetinitis Pigmentosa Rp1 Protein |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCilium AxonemeCell ProjectionCiliumPhotoreceptor Outer SegmentSpecifically Localized In The Connecting Cilia Of Rod And Cone Photoreceptors |
| Alternative Antibody Names | Anti-Oxygen-Regulated Protein 1 antibodyAnti-Retinitis Pigmentosa 1 Protein antibodyAnti-Retinitis Pigmentosa Rp1 Protein antibodyAnti-RP1 antibodyAnti-ORP1 antibody |
Information sourced from Uniprot.org