| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RP1 |
| Gene ID: | 6101 |
| Uniprot ID: | RP1_HUMAN |
| Immunogen Region: | 250-500 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-500 of human RP1 (NP_006260.1). |
| Immunogen Sequence: | VYPKGNAKSESRKISTHMSS SSRSQIYSVSSEKTHNNDCY LDYSFVPEKYLALEKNDSQN LPIYPSEDDIEKSIIFNQDG TMTVEMKVRFRIKEEETIKW TTTVSKTGPSNNDEKSEMSF PGRTESRSSGLKLAACSFSA DVSPMERSSNQEGSLAEEIN IQMTDQVAETCSSASWENAT VDTDIIQGTQDQAKHRFYRP PTPGLRRVRQKKSVIGSVTL VSETEVQEKMIGQFSYSEE |
| Tissue Specificity | Expressed in retina. Not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, spleen and pancreas. |
| Function | Microtubule-associated protein regulating the stability and length of the microtubule-based axoneme of photoreceptors. Required for the differentiation of photoreceptor cells, it plays a role in the organization of the outer segment of rod and cone photoreceptors ensuring the correct orientation and higher-order stacking of outer segment disks along the photoreceptor axoneme. |
| Protein Name | Oxygen-Regulated Protein 1Retinitis Pigmentosa 1 ProteinRetinitis Pigmentosa Rp1 Protein |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCilium AxonemeCell ProjectionCiliumPhotoreceptor Outer SegmentSpecifically Localized In The Connecting Cilia Of Rod And Cone Photoreceptors |
| Alternative Antibody Names | Anti-Oxygen-Regulated Protein 1 antibodyAnti-Retinitis Pigmentosa 1 Protein antibodyAnti-Retinitis Pigmentosa Rp1 Protein antibodyAnti-RP1 antibodyAnti-ORP1 antibody |
Information sourced from Uniprot.org
