Anti-RP1 antibody (250-500 aa) (STJ11106365)

SKU:
STJ11106365
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: RP1
Gene ID: 6101
Uniprot ID: RP1_HUMAN
Immunogen Region: 250-500 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 250-500 of human RP1 (NP_006260.1).
Immunogen Sequence: VYPKGNAKSESRKISTHMSS SSRSQIYSVSSEKTHNNDCY LDYSFVPEKYLALEKNDSQN LPIYPSEDDIEKSIIFNQDG TMTVEMKVRFRIKEEETIKW TTTVSKTGPSNNDEKSEMSF PGRTESRSSGLKLAACSFSA DVSPMERSSNQEGSLAEEIN IQMTDQVAETCSSASWENAT VDTDIIQGTQDQAKHRFYRP PTPGLRRVRQKKSVIGSVTL VSETEVQEKMIGQFSYSEE
Tissue Specificity Expressed in retina. Not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, spleen and pancreas.
Function Microtubule-associated protein regulating the stability and length of the microtubule-based axoneme of photoreceptors. Required for the differentiation of photoreceptor cells, it plays a role in the organization of the outer segment of rod and cone photoreceptors ensuring the correct orientation and higher-order stacking of outer segment disks along the photoreceptor axoneme.
Protein Name Oxygen-Regulated Protein 1
Retinitis Pigmentosa 1 Protein
Retinitis Pigmentosa Rp1 Protein
Cellular Localisation Cytoplasm
Cytoskeleton
Cilium Axoneme
Cell Projection
Cilium
Photoreceptor Outer Segment
Specifically Localized In The Connecting Cilia Of Rod And Cone Photoreceptors
Alternative Antibody Names Anti-Oxygen-Regulated Protein 1 antibody
Anti-Retinitis Pigmentosa 1 Protein antibody
Anti-Retinitis Pigmentosa Rp1 Protein antibody
Anti-RP1 antibody
Anti-ORP1 antibody

Information sourced from Uniprot.org