Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Gene Symbol: | RP1 |
Gene ID: | 6101 |
Uniprot ID: | RP1_HUMAN |
Immunogen Region: | 250-500 aa |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-500 of human RP1 (NP_006260.1). |
Immunogen Sequence: | VYPKGNAKSESRKISTHMSS SSRSQIYSVSSEKTHNNDCY LDYSFVPEKYLALEKNDSQN LPIYPSEDDIEKSIIFNQDG TMTVEMKVRFRIKEEETIKW TTTVSKTGPSNNDEKSEMSF PGRTESRSSGLKLAACSFSA DVSPMERSSNQEGSLAEEIN IQMTDQVAETCSSASWENAT VDTDIIQGTQDQAKHRFYRP PTPGLRRVRQKKSVIGSVTL VSETEVQEKMIGQFSYSEE |
Tissue Specificity | Expressed in retina. Not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, spleen and pancreas. |
Function | Microtubule-associated protein regulating the stability and length of the microtubule-based axoneme of photoreceptors. Required for the differentiation of photoreceptor cells, it plays a role in the organization of the outer segment of rod and cone photoreceptors ensuring the correct orientation and higher-order stacking of outer segment disks along the photoreceptor axoneme. |
Protein Name | Oxygen-Regulated Protein 1Retinitis Pigmentosa 1 ProteinRetinitis Pigmentosa Rp1 Protein |
Cellular Localisation | CytoplasmCytoskeletonCilium AxonemeCell ProjectionCiliumPhotoreceptor Outer SegmentSpecifically Localized In The Connecting Cilia Of Rod And Cone Photoreceptors |
Alternative Antibody Names | Anti-Oxygen-Regulated Protein 1 antibodyAnti-Retinitis Pigmentosa 1 Protein antibodyAnti-Retinitis Pigmentosa Rp1 Protein antibodyAnti-RP1 antibodyAnti-ORP1 antibody |
Information sourced from Uniprot.org