Anti-ROPN1 antibody (85-135 aa) (STJ195586)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ROP1A at the amino acid range 85-135
General Information
| Short Description | Rabbit polyclonal anti-Ropporin-1A (85-135 aa) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ROPN1 |
| Gene ID | 54763 |
| Uniprot ID | ROP1A_HUMAN |
| Immunogen | Synthesized peptide derived from the human ROP1A at the amino acid range 85-135 |
| Immunogen Region | 85-135 aa |
| Specificity | This antibody detects endogenous levels of ROP1A at Human |
Additional Info
| Post Translational Modifications | Sumoylated, sumoylation decreases upon spermatozoa capacitation conditions. |
| Function | Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation. |
| Protein Name | Ropporin-1aCancer/Testis Antigen 91Ct91Rhophilin-Associated Protein 1a |
| Database Links | Reactome: R-HSA-5666185 |
| Cellular Localisation | Cell ProjectionCiliumFlagellumIn The Sperm TailFound In The Principal Piece And In The Cytoplasmic Droplet Located At The Distal End Of The MidpieceInner Surface Of The Fibrous Sheath |
| Alternative Antibody Names | Anti-Ropporin-1a antibodyAnti-Cancer/Testis Antigen 91 antibodyAnti-Ct91 antibodyAnti-Rhophilin-Associated Protein 1a antibodyAnti-ROPN1 antibodyAnti-ROPN1A antibody |
Information sourced from Uniprot.org