| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Ropporin-1A (85-135 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ROPN1 |
| Gene ID: |
54763 |
| Uniprot ID: |
ROP1A_HUMAN |
| Immunogen Region: |
85-135 aa |
| Specificity: |
This antibody detects endogenous levels of ROP1A at Human |
| Immunogen: |
Synthesized peptide derived from the human ROP1A at the amino acid range 85-135 |
| Post Translational Modifications | Sumoylated, sumoylation decreases upon spermatozoa capacitation conditions. |
| Function | Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation. |
| Protein Name | Ropporin-1aCancer/Testis Antigen 91Ct91Rhophilin-Associated Protein 1a |
| Database Links | Reactome: R-HSA-5666185 |
| Cellular Localisation | Cell ProjectionCiliumFlagellumIn The Sperm TailFound In The Principal Piece And In The Cytoplasmic Droplet Located At The Distal End Of The MidpieceInner Surface Of The Fibrous Sheath |
| Alternative Antibody Names | Anti-Ropporin-1a antibodyAnti-Cancer/Testis Antigen 91 antibodyAnti-Ct91 antibodyAnti-Rhophilin-Associated Protein 1a antibodyAnti-ROPN1 antibodyAnti-ROPN1A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
