| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ROBO4 |
| Gene ID: | 54538 |
| Uniprot ID: | ROBO4_HUMAN |
| Immunogen Region: | 848-1007 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 848-1007 of human ROBO4 (NP_061928.4). |
| Immunogen Sequence: | GVGPKGGVLLCPPRPCLTPT PSEGSLANGWGSASEDNAAS ARASLVSSSDGSFLADAHFA RALAVAVDSFGFGLEPREAD CVFIDASSPPSPRDEIFLTP NLSLPLWEWRPDWLEDMEVS HTQRLGRGMPPWPPDSQISS QRSQLHCRMPKAGASPVDYS |
| Tissue Specificity | Specifically expressed in endothelial cells. Expressed in endothelial and intimal cells of the ascending aorta. |
| Function | Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins. Involved in the maintenance of endothelial barrier organization and function. |
| Protein Name | Roundabout Homolog 4Magic Roundabout |
| Alternative Antibody Names | Anti-Roundabout Homolog 4 antibodyAnti-Magic Roundabout antibodyAnti-ROBO4 antibodyAnti-UNQ421 antibodyAnti-PRO3674 antibody |
Information sourced from Uniprot.org