| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Ribonuclease inhibitor (273-323 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RNH1 |
| Gene ID: |
6050 |
| Uniprot ID: |
RINI_HUMAN |
| Immunogen Region: |
273-323 aa |
| Specificity: |
This antibody detects endogenous levels of RINI at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human RINI at the amino acid range 273-323 |
| Function | Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and angiogenin (ANG). May play a role in redox homeostasis. Required to inhibit the cytotoxic tRNA ribonuclease activity of ANG in the cytoplasm in absence of stress. Relocates to the nucleus in response to stress, relieving inhibition of ANG in the cytoplasm, and inhibiting the angiogenic activity of ANG in the nucleus. |
| Protein Name | Ribonuclease InhibitorPlacental Ribonuclease InhibitorPlacental Rnase InhibitorRibonuclease/Angiogenin Inhibitor 1Rai |
| Cellular Localisation | CytoplasmNucleusLocalizes In The Cytoplasm In Absence Of StressTranslocates To The Nucleus In Response To Stress |
| Alternative Antibody Names | Anti-Ribonuclease Inhibitor antibodyAnti-Placental Ribonuclease Inhibitor antibodyAnti-Placental Rnase Inhibitor antibodyAnti-Ribonuclease/Angiogenin Inhibitor 1 antibodyAnti-Rai antibodyAnti-RNH1 antibodyAnti-PRI antibodyAnti-RNH antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
