| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC/FC |
| Reactivity: |
Human/Mouse/Rat/Dog/Pig/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-RNF13/RZF-Isoform 1/3 (C-Term) is suitable for use in ELISA, Western Blot, Immunohistochemistry and Flow Cytometry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
ELISA-antibody detection limit dilution 1:1000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
RNF13 |
| Gene ID: |
11342 |
| Uniprot ID: |
RNF13_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_009213.1 |
| Specificity: |
Reported variants represent identical protein (NP_009213.1; NP_899237.1). |
| Immunogen Sequence: |
PNGERDYNIANTV |
| Post Translational Modifications | Autoubiquitinated. |
| Function | E3 ubiquitin-protein ligase that regulates cell proliferation. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA. Also involved in protein trafficking and localization. |
| Protein Name | E3 Ubiquitin-Protein Ligase Rnf13Ring Finger Protein 13 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane ProteinLate Endosome MembraneLysosome MembraneNucleus Inner MembraneUnder Certain ConditionsRelocalizes To Recycling Endosomes And To The Inner Nuclear Membrane |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Rnf13 antibodyAnti-Ring Finger Protein 13 antibodyAnti-RNF13 antibodyAnti-RZF antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
