Anti-RND1 antibody (140-220 aa) (STJ191330)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 140-220
General Information
| Short Description | Rabbit polyclonal anti-Rho-related GTP-binding protein Rho6 (140-220 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RND1 |
| Gene ID | 27289 |
| Uniprot ID | RND1_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 140-220 |
| Immunogen Region | 140-220 aa |
| Specificity | RND1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments. |
| Protein Name | Rho-Related Gtp-Binding Protein Rho6Rho Family Gtpase 1Rnd1 |
| Database Links | Reactome: R-HSA-399955Reactome: R-HSA-416550Reactome: R-HSA-416572Reactome: R-HSA-9696273 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideCytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Rho-Related Gtp-Binding Protein Rho6 antibodyAnti-Rho Family Gtpase 1 antibodyAnti-Rnd1 antibodyAnti-RND1 antibodyAnti-RHO6 antibody |
Information sourced from Uniprot.org