• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-RNASEK antibody (27-77 aa) (STJ196630)

SKU:
STJ196630

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Ribonuclease kappa (27-77 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RNASEK
Gene ID: 440400
Uniprot ID: RNK_HUMAN
Immunogen Region: 27-77 aa
Specificity: This antibody detects endogenous levels of RNK at Human/Mouse
Immunogen: Synthesized peptide derived from the human RNK at the amino acid range 27-77
Function Endoribonuclease which preferentially cleaves ApU and ApG phosphodiester bonds. Hydrolyzes UpU bonds at a lower rate. Regulates the activity of vacuolar (H+)-ATPase (V-ATPase) which is responsible for acidifying and maintaining the pH of intracellular compartments. Required at an early stage of receptor-mediated endocytosis. (Microbial infection) Required at an early stage of both clathrin-mediated and clathrin-independent endocytic uptake of a diverse set of viruses, including dengue, West Nile, Sindbis, Rift Valley Fever, influenza, and human rhinoviruses.
Protein Name Ribonuclease Kappa
Rnase K
Rnase Kappa
V-Type Proton Atpase Subunit F
V-Atpase Subunit F
Cellular Localisation Endomembrane System
Multi-Pass Membrane Protein
Cytoplasmic Vesicle
Clathrin-Coated Vesicle Membrane
Alternative Antibody Names Anti-Ribonuclease Kappa antibody
Anti-Rnase K antibody
Anti-Rnase Kappa antibody
Anti-V-Type Proton Atpase Subunit F antibody
Anti-V-Atpase Subunit F antibody
Anti-RNASEK antibody

Information sourced from Uniprot.org

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