Anti-RNASEH2C antibody (1-164) (STJ115823)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RNASEH2C (1-164) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RNASEH2C |
| Gene ID | 84153 |
| Uniprot ID | RNH2C_HUMAN |
| Immunogen Region | 1-164 |
| Immunogen Sequence | MESGDEAAIERHRVHLRSAT LRDAVPATLHLLPCEVAVDG PAPVGRFFTPAIRQGPEGLE VSFRGRCLRGEEVAVPPGLV GYVMVTEEKKVSMGKPDPLR DSGTDDQEEEPLERDFDRFI GATANFSRFTLWGLETIPGP DAKVRGALTWPSLAAAIHAQ VPED |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human RNASEH2C (NP_115569.2). |
Additional Info
| Tissue Specificity | Widely expressed. |
| Function | Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. |
| Protein Name | Ribonuclease H2 Subunit CRnase H2 Subunit CAicardi-Goutieres Syndrome 3 ProteinAgs3Rnase H1 Small SubunitRibonuclease Hi Subunit C |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ribonuclease H2 Subunit C antibodyAnti-Rnase H2 Subunit C antibodyAnti-Aicardi-Goutieres Syndrome 3 Protein antibodyAnti-Ags3 antibodyAnti-Rnase H1 Small Subunit antibodyAnti-Ribonuclease Hi Subunit C antibodyAnti-RNASEH2C antibodyAnti-AYP1 antibody |
Information sourced from Uniprot.org