Anti-RNASEH2A antibody (1-299) (STJ117326)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RNASEH2A (1-299) antibody for use in WB, IF, ICC and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RNASEH2A |
| Gene ID | 10535 |
| Uniprot ID | RNH2A_HUMAN |
| Immunogen Region | 1-299 |
| Immunogen Sequence | MDLSELERDNTGRCRLSSPV PAVCRKEPCVLGVDEAGRGP VLGPMVYAICYCPLPRLADL EALKVADSKTLLESERERLF AKMEDTDFVGWALDVLSPNL ISTSMLGRVKYNLNSLSHDT ATGLIQYALDQGVNVTQVFV DTVGMPETYQARLQQSFPGI EVTVKAKADALYPVVSAASI CAKVARDQAVKKWQFVEKLQ DLDTDYGSGYPNDPKTKAWL KEHVEPVFGFPQFVRFSWR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human RNASEH2A (NP_006388.2). |
Additional Info
| Function | Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. |
| Protein Name | Ribonuclease H2 Subunit ARnase H2 Subunit AAicardi-Goutieres Syndrome 4 ProteinAgs4Rnase H(35Ribonuclease Hi Large SubunitRnase Hi Large SubunitRibonuclease Hi Subunit A |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ribonuclease H2 Subunit A antibodyAnti-Rnase H2 Subunit A antibodyAnti-Aicardi-Goutieres Syndrome 4 Protein antibodyAnti-Ags4 antibodyAnti-Rnase H(35 antibodyAnti-Ribonuclease Hi Large Subunit antibodyAnti-Rnase Hi Large Subunit antibodyAnti-Ribonuclease Hi Subunit A antibodyAnti-RNASEH2A antibodyAnti-RNASEHI antibodyAnti-RNHIA antibody |
Information sourced from Uniprot.org