Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-RNASEH2A (1-299) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
RNASEH2A |
Gene ID: |
10535 |
Uniprot ID: |
RNH2A_HUMAN |
Immunogen Region: |
1-299 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human RNASEH2A (NP_006388.2). |
Immunogen Sequence: |
MDLSELERDNTGRCRLSSPV PAVCRKEPCVLGVDEAGRGP VLGPMVYAICYCPLPRLADL EALKVADSKTLLESERERLF AKMEDTDFVGWALDVLSPNL ISTSMLGRVKYNLNSLSHDT ATGLIQYALDQGVNVTQVFV DTVGMPETYQARLQQSFPGI EVTVKAKADALYPVVSAASI CAKVARDQAVKKWQFVEKLQ DLDTDYGSGYPNDPKTKAWL KEHVEPVFGFPQFVRFSWR |
Function | Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. |
Protein Name | Ribonuclease H2 Subunit ARnase H2 Subunit AAicardi-Goutieres Syndrome 4 ProteinAgs4Rnase H(35Ribonuclease Hi Large SubunitRnase Hi Large SubunitRibonuclease Hi Subunit A |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Ribonuclease H2 Subunit A antibodyAnti-Rnase H2 Subunit A antibodyAnti-Aicardi-Goutieres Syndrome 4 Protein antibodyAnti-Ags4 antibodyAnti-Rnase H(35 antibodyAnti-Ribonuclease Hi Large Subunit antibodyAnti-Rnase Hi Large Subunit antibodyAnti-Ribonuclease Hi Subunit A antibodyAnti-RNASEH2A antibodyAnti-RNASEHI antibodyAnti-RNHIA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance