Host: | Rabbit |
Applications: | WB/ELISA/IHC |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Ribonuclease 7 (37-87 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | RNASE7 |
Gene ID: | 84659 |
Uniprot ID: | RNAS7_HUMAN |
Immunogen Region: | 37-87 aa |
Specificity: | This antibody detects endogenous levels of RNAS7 at Human |
Immunogen: | Synthesized peptide derived from the human RNAS7 at the amino acid range 37-87 |
Function | Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Causes loss of bacterial membrane integrity. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity. |
Protein Name | Ribonuclease 7Rnase 7Skin-Derived Antimicrobial Protein 2Sap-2 |
Database Links | Reactome: R-HSA-6803157 |
Cellular Localisation | SecretedDetected In Urine |
Alternative Antibody Names | Anti-Ribonuclease 7 antibodyAnti-Rnase 7 antibodyAnti-Skin-Derived Antimicrobial Protein 2 antibodyAnti-Sap-2 antibodyAnti-RNASE7 antibodyAnti-UNQ2516 antibodyAnti-PRO6006 antibody |
Information sourced from Uniprot.org