Anti-RNASE3 antibody (28-160) (STJ25365)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RNASE3 (28-160) antibody for use in IHC-P and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RNASE3 |
| Gene ID | 6037 |
| Uniprot ID | ECP_HUMAN |
| Immunogen Region | 28-160 |
| Immunogen Sequence | RPPQFTRAQWFAIQHISLNP PRCTIAMRAINNYRWRCKNQ NTFLRTTFANVVNVCGNQSI RCPHNRTLNNCHRSRFRVPL LHCDLINPGAQNISNCTYAD RPGRRFYVVACDNRDPRDSP RYPVVPVHLDTTI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 28-160 of human RNASE3 (NP_002926.2). |
Additional Info
| Function | Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. |
| Protein Name | Eosinophil Cationic ProteinEcpRibonuclease 3Rnase 3 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-6803157 |
| Cellular Localisation | SecretedLocated In The Matrix Of Eosinophil Large Specific GranuleWhich Are Released Following Activation By An Immune Stimulus |
| Alternative Antibody Names | Anti-Eosinophil Cationic Protein antibodyAnti-Ecp antibodyAnti-Ribonuclease 3 antibodyAnti-Rnase 3 antibodyAnti-RNASE3 antibodyAnti-ECP antibodyAnti-RNS3 antibody |
Information sourced from Uniprot.org