| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RMND5A (200-270) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RMND5A |
| Gene ID: |
64795 |
| Uniprot ID: |
RMD5A_HUMAN |
| Immunogen Region: |
200-270 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 200-270 of human RMND5A (NP_073617.1). |
| Immunogen Sequence: |
ISLLMGGTTNQREALQYAKN FQPFALNHQKDIQVLMGSLV YLRQGIENSPYVHLLDANQW ADICDIFTRDA |
| Function | Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. Catalytic activity of the complex is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1. |
| Protein Name | E3 Ubiquitin-Protein Transferase Rmnd5aP44ctlhProtein Rmd5 Homolog A |
| Cellular Localisation | NucleusNucleoplasmCytoplasm |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Transferase Rmnd5a antibodyAnti-P44ctlh antibodyAnti-Protein Rmd5 Homolog A antibodyAnti-RMND5A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
