| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-GTP-binding protein Rit1 (170-219 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RIT1 |
| Gene ID: | 6016 |
| Uniprot ID: | RIT1_HUMAN |
| Immunogen Region: | 170-219 aa |
| Specificity: | Rit1 Polyclonal Antibody detects endogenous levels of Rit1 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human RIT1 at the amino acid range 170-219 |
| Function | Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation. |
| Protein Name | Gtp-Binding Protein Rit1Ras-Like Protein Expressed In Many TissuesRas-Like Without Caax Protein 1 |
| Database Links | Reactome: R-HSA-187706 |
| Cellular Localisation | Cell Membrane |
| Alternative Antibody Names | Anti-Gtp-Binding Protein Rit1 antibodyAnti-Ras-Like Protein Expressed In Many Tissues antibodyAnti-Ras-Like Without Caax Protein 1 antibodyAnti-RIT1 antibodyAnti-RIBB antibodyAnti-RIT antibodyAnti-ROC1 antibody |
Information sourced from Uniprot.org