• Western blot analysis of the lysates from HeLa cells using RIOK3 antibody.
  • Western blot analysis of lysates from HepG2 cells, using RIOK3 Antibody. The lane on the right is blocked with the synthesized peptide.

Anti-RIOK3 antibody (271-320 aa) (STJ95831)

SKU:
STJ95831

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Serine/threonine-protein kinase RIO3 (271-320 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RIOK3
Gene ID: 8780
Uniprot ID: RIOK3_HUMAN
Immunogen Region: 271-320 aa
Specificity: SUDD Polyclonal Antibody detects endogenous levels of SUDD protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human RIOK3 at the amino acid range 271-320
Post Translational Modifications Autophosphorylated (in vitro).
Function Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. May act as an adapter protein essential for the recruitment of TBK1 to IRF3. Phosphorylates IFIH1 on 'Ser-828' interfering with IFIH1 filament assembly on long dsRNA and resulting in attenuated IFIH1-signaling. Can inhibit CASP10 isoform 7-mediated activation of the NF-kappaB signaling pathway. May play a role in the biogenesis of the 40S ribosomal subunit. Involved in the processing of 21S pre-rRNA to the mature 18S rRNA.
Protein Name Serine/Threonine-Protein Kinase Rio3
Rio Kinase 3
Sudd Homolog
Database Links Reactome: R-HSA-6791226
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Serine/Threonine-Protein Kinase Rio3 antibody
Anti-Rio Kinase 3 antibody
Anti-Sudd Homolog antibody
Anti-RIOK3 antibody
Anti-SUDD antibody

Information sourced from Uniprot.org

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