Anti-RIG1/RARRES3 antibody (124-136) (STJ71469)

SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
STJ71469-100
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General Information

Short DescriptionGoat polyclonal antibody anti-RIG1/RARRES3 (124-136) is suitable for use in ELISA and Immunohistochemistry research applications.
ApplicationsPep-ELISA/IHC
HostGoat
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration0.5 mg/mL
PurificationPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution RangePeptide ELISA: antibody detection limit dilution 1:128000.
WB: Preliminary experiments gave bands at approx 22kDa and 55kDa in Human Thymus lysates after 1ยตg/ml antibody staining. The 55kDa band was observed in all tissues tested. Please note tha
Formulation0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage InstructionStore at-20ยฐC on receipt and minimise freeze-thaw cycles.

Target Information

Gene SymbolPLAAT4
Gene ID5920
Uniprot IDPLAT4_HUMAN
Accession NumberNP_004576.2
Immunogen Region124-136
Immunogen SequenceKSRCKQVEKAKVE

Additional Info

Function Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2), catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. For most substrates, PLA1 activity is much higher than PLA2 activity. Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE), which serves as precursor for N-acylethanolamines (NAEs). Promotes keratinocyte differentiation via activation of TGM1.
Protein Name Phospholipase A And Acyltransferase 4
Hras-Like Suppressor 4
Hrsl4
Rar-Responsive Protein Tig3
Retinoic Acid Receptor Responder Protein 3
Retinoid-Inducible Gene 1 Protein
Tazarotene-Induced Gene 3 Protein
Database Links Reactome: R-HSA-1482839
Cellular Localisation Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Phospholipase A And Acyltransferase 4 antibody
Anti-Hras-Like Suppressor 4 antibody
Anti-Hrsl4 antibody
Anti-Rar-Responsive Protein Tig3 antibody
Anti-Retinoic Acid Receptor Responder Protein 3 antibody
Anti-Retinoid-Inducible Gene 1 Protein antibody
Anti-Tazarotene-Induced Gene 3 Protein antibody
Anti-PLAAT4 antibody
Anti-RARRES3 antibody
Anti-RIG1 antibody
Anti-TIG3 antibody

Information sourced from Uniprot.org

Citations

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