| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-RIG1/RARRES3 (124-136) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000. WB: Preliminary experiments gave bands at approx 22kDa and 55kDa in Human Thymus lysates after 1µg/ml antibody staining. The 55kDa band was observed in all tissues tested. Please note tha |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | PLAAT4 |
| Gene ID: | 5920 |
| Uniprot ID: | PLAT4_HUMAN |
| Immunogen Region: | 124-136 |
| Accession Number: | NP_004576.2 |
| Immunogen Sequence: | KSRCKQVEKAKVE |
| Function | Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2), catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. For most substrates, PLA1 activity is much higher than PLA2 activity. Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE), which serves as precursor for N-acylethanolamines (NAEs). Promotes keratinocyte differentiation via activation of TGM1. |
| Protein Name | Phospholipase A And Acyltransferase 4 Hras-Like Suppressor 4 Hrsl4 Rar-Responsive Protein Tig3 Retinoic Acid Receptor Responder Protein 3 Retinoid-Inducible Gene 1 Protein Tazarotene-Induced Gene 3 Protein |
| Database Links | Reactome: R-HSA-1482839 |
| Cellular Localisation | Membrane Single-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Phospholipase A And Acyltransferase 4 antibody Anti-Hras-Like Suppressor 4 antibody Anti-Hrsl4 antibody Anti-Rar-Responsive Protein Tig3 antibody Anti-Retinoic Acid Receptor Responder Protein 3 antibody Anti-Retinoid-Inducible Gene 1 Protein antibody Anti-Tazarotene-Induced Gene 3 Protein antibody Anti-PLAAT4 antibody Anti-RARRES3 antibody Anti-RIG1 antibody Anti-TIG3 antibody |
Information sourced from Uniprot.org