Anti-RHOT2 antibody (STJA0006838)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human MIRO2
General Information
| Short Description | Rabbit polyclonal anti-Mitochondrial Rho GTPase 2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RHOT2 |
| Gene ID | 89941 |
| Uniprot ID | MIRO2_HUMAN |
| Immunogen | Synthesized peptide derived from human MIRO2 |
| Specificity | This antibody detects endogenous levels of MIRO2 at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Ubiquitinated by PRKN in a PINK1-dependent manner, leading to its degradation. |
| Function | Atypical mitochondrial nucleoside-triphosphatase (NTPase) involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. Can hydrolyze GTP. Can hydrolyze ATP and UTP. |
| Protein Name | Mitochondrial Rho Gtpase 2Miro-2Hmiro-2Ras Homolog Gene Family Member T2 |
| Database Links | Reactome: R-HSA-9013419 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iv Membrane ProteinColocalizes With Mgarp And Rhot2 At The Mitochondria |
| Alternative Antibody Names | Anti-Mitochondrial Rho Gtpase 2 antibodyAnti-Miro-2 antibodyAnti-Hmiro-2 antibodyAnti-Ras Homolog Gene Family Member T2 antibodyAnti-RHOT2 antibodyAnti-ARHT2 antibodyAnti-C16orf39 antibody |
Information sourced from Uniprot.org