| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
RHOJ |
| Gene ID: |
57381 |
| Uniprot ID: |
RHOJ_HUMAN |
| Immunogen Region: |
145-214 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 145-214 of human RHOJ (NP_065714.1). |
| Immunogen Sequence: |
ARLLYMKEKPLTYEHGVKLA KAIGAQCYLECSALTQKGLK AVFDEAILTIFHPKKKKKRC SEGHSCCSII |
| Tissue Specificity | Specifically expressed in endothelial cells in different tissues, such as brain, heart, lung and liver. |
| Post Translational Modifications | Palmitoylated.regulates localization to the plasma membrane and may be mediated by GLUL. |
| Function | Plasma membrane-associated small GTPase specifically involved in angiogenesis. Required for endothelial cell migration during vascular development via its interaction with GLUL. Elicits the formation of F-actin-rich structures, thereby regulating endothelial cell migration. |
| Protein Name | Rho-Related Gtp-Binding Protein RhojRas-Like Protein Family Member 7bTc10-Like Gtp-Binding Protein |
| Database Links | Reactome: R-HSA-9013409 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideLocalization To The Plasma Membrane Is Regulated By Glul |
| Alternative Antibody Names | Anti-Rho-Related Gtp-Binding Protein Rhoj antibodyAnti-Ras-Like Protein Family Member 7b antibodyAnti-Tc10-Like Gtp-Binding Protein antibodyAnti-RHOJ antibodyAnti-ARHJ antibodyAnti-RASL7B antibodyAnti-RHOI antibodyAnti-TCL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
