Anti-RHCG antibody (Internal) (STJ96453)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the Internal region of human RhCG.
General Information
| Short Description | Rabbit polyclonal anti-Ammonium transporter Rh type C (Internal) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC-P 1:100-300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RHCG |
| Gene ID | 51458 |
| Uniprot ID | RHCG_HUMAN |
| Immunogen | Synthesized peptide derived from the Internal region of human RhCG. |
| Immunogen Region | Internal |
| Specificity | RhCG Polyclonal Antibody detects endogenous levels of RhCG protein. |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Ammonium transporter involved in the maintenance of acid-base homeostasis. Transports ammonium and its related derivative methylammonium across the plasma membrane of epithelial cells likely contributing to renal transepithelial ammonia transport and ammonia metabolism. Postulated to primarily mediate an electroneutral bidirectional transport of NH3 ammonia species according to a mechanism that implies interaction of an NH4(+) ion with acidic residues of the pore entry followed by dissociation of NH4(+) into NH3 and H(+). As a result NH3 transits through the central pore and is protonated on the extracellular side reforming NH4(+). May act as a CO2 channel providing for renal acid secretion. |
| Protein Name | Ammonium Transporter Rh Type CRh Glycoprotein KidneyRhesus Blood Group Family Type C GlycoproteinRh Family Type C GlycoproteinRh Type C GlycoproteinTumor-Related Protein Drc2 |
| Database Links | Reactome: R-HSA-444411 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell MembraneAlso Detected At The Basolateral Membrane And In Subapical Vesicles |
| Alternative Antibody Names | Anti-Ammonium Transporter Rh Type C antibodyAnti-Rh Glycoprotein Kidney antibodyAnti-Rhesus Blood Group Family Type C Glycoprotein antibodyAnti-Rh Family Type C Glycoprotein antibodyAnti-Rh Type C Glycoprotein antibodyAnti-Tumor-Related Protein Drc2 antibodyAnti-RHCG antibodyAnti-C15orf6 antibodyAnti-CDRC2 antibodyAnti-PDRC2 antibodyAnti-RHGK antibody |
Information sourced from Uniprot.org