| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human/Dog/Pig |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-RHCG (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 60kDa band observed in Human Testis lysates (calculated MW of 53.2kDa according to NP_057405.1). The observed molecular weight corresponds to earlier findings in literature with |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
RHCG |
| Gene ID: |
51458 |
| Uniprot ID: |
RHCG_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_057405.1 |
| Immunogen Sequence: |
ERQNSVYQSD |
| Post Translational Modifications | N-glycosylated. |
| Function | Ammonium transporter involved in the maintenance of acid-base homeostasis. Transports ammonium and its related derivative methylammonium across the plasma membrane of epithelial cells likely contributing to renal transepithelial ammonia transport and ammonia metabolism. Postulated to primarily mediate an electroneutral bidirectional transport of NH3 ammonia species according to a mechanism that implies interaction of an NH4(+) ion with acidic residues of the pore entry followed by dissociation of NH4(+) into NH3 and H(+). As a result NH3 transits through the central pore and is protonated on the extracellular side reforming NH4(+). May act as a CO2 channel providing for renal acid secretion. |
| Protein Name | Ammonium Transporter Rh Type CRh Glycoprotein KidneyRhesus Blood Group Family Type C GlycoproteinRh Family Type C GlycoproteinRh Type C GlycoproteinTumor-Related Protein Drc2 |
| Database Links | Reactome: R-HSA-444411 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell MembraneAlso Detected At The Basolateral Membrane And In Subapical Vesicles |
| Alternative Antibody Names | Anti-Ammonium Transporter Rh Type C antibodyAnti-Rh Glycoprotein Kidney antibodyAnti-Rhesus Blood Group Family Type C Glycoprotein antibodyAnti-Rh Family Type C Glycoprotein antibodyAnti-Rh Type C Glycoprotein antibodyAnti-Tumor-Related Protein Drc2 antibodyAnti-RHCG antibodyAnti-C15orf6 antibodyAnti-CDRC2 antibodyAnti-PDRC2 antibodyAnti-RHGK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
