Anti-RGS6 antibody (443-455 aa) [R02-1D3] (STJA0012572)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human RGS6
General Information
| Short Description | Rabbit monoclonal anti-RGS6 (443-455 aa) for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-1D3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4ยฐC short term. Aliquot and store at-20ยฐC long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | RGS6 |
| Gene ID | 9628 |
| Uniprot ID | RGS6_HUMAN |
| Immunogen | A synthetic peptide of human RGS6 |
| Immunogen Region | 443-455 aa |
Additional Info
| Function | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity. |
| Protein Name | Regulator Of G-Protein Signaling 6Rgs6S914 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-6814122 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinNucleusCell MembraneInteraction With Gnb5 Mediates Translocation To The Nucleus |
| Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 6 antibodyAnti-Rgs6 antibodyAnti-S914 antibodyAnti-RGS6 antibody |
Information sourced from Uniprot.org