| Short Description : | Rabbit polyclonal anti-Regulator of G-protein signaling 4 (80-160 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RGS4 |
| Gene ID: | 5999 |
| Uniprot ID: | RGS4_HUMAN |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 80-160 |
| Immunogen Region: | 80-160 aa |
| Specificity: | RGS4 Polyclonal Antibody detects endogenous levels of protein. |
| Post Translational Modifications | Palmitoylated on Cys-2 and/or Cys-12. Phosphorylated by cyclic GMP-dependent protein kinase. |
| Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein. |
| Protein Name | Regulator Of G-Protein Signaling 4Rgp4Rgs4 |
| Database Links | Reactome: R-HSA-416476Reactome: R-HSA-418594Reactome: R-HSA-418597 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 4 antibodyAnti-Rgp4 antibodyAnti-Rgs4 antibodyAnti-RGS4 antibody |
Information sourced from Uniprot.org
