| Tissue Specificity | Expressed in brain and heart. Expressed in brain at protein level. Expressed in prefontal and visual cortex. Isoform 4 and isoform 5 are expressed ubiquitously. Isoform 1, isoform 2 and isoform 3 are not expressed in the cerebellum. |
| Post Translational Modifications | Palmitoylated on Cys-2 and/or Cys-12. Phosphorylated by cyclic GMP-dependent protein kinase. |
| Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein. |
| Protein Name | Regulator Of G-Protein Signaling 4Rgp4Rgs4 |
| Database Links | Reactome: R-HSA-416476Reactome: R-HSA-418594Reactome: R-HSA-418597 |
| Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 4 antibodyAnti-Rgp4 antibodyAnti-Rgs4 antibodyAnti-RGS4 antibody |
Information sourced from Uniprot.org
