| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Regulator of G-protein signaling 3 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RGS3 |
| Gene ID: | 5998 |
| Uniprot ID: | RGS3_HUMAN |
| Specificity: | This antibody detects endogenous levels of RGS3 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human RGS3 |
| Function | Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases. |
| Protein Name | Regulator Of G-Protein Signaling 3Rgp3Rgs3 |
| Database Links | Reactome: R-HSA-416476Reactome: R-HSA-418594 |
| Cellular Localisation | CytoplasmNucleusCell MembranePeripheral Membrane ProteinLong Isoforms Are Cytoplasmic And Associated With The Plasma MembraneShort Isoforms Are Nuclear |
| Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 3 antibodyAnti-Rgp3 antibodyAnti-Rgs3 antibodyAnti-RGS3 antibody |
Information sourced from Uniprot.org