| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RGN |
| Gene ID: | 9104 |
| Uniprot ID: | RGN_HUMAN |
| Immunogen Region: | 1-299 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human RGN (NP_004674.1). |
| Immunogen Sequence: | MSSIKIECVLPENCRCGESP VWEEVSNSLLFVDIPAKKVC RWDSFTKQVQRVTMDAPVSS VALRQSGGYVATIGTKFCAL NWKEQSAVVLATVDNDKKNN RFNDGKVDPAGRYFAGTMAE ETAPAVLERHQGALYSLFPD HHVKKYFDQVDISNGLDWSL DHKIFYYIDSLSYSVDAFDY DLQTGQISNRRSVYKLEKEE QIPDGMCIDAEGKLWVACYN GGRVIRLDPVTGKRLQTVK |
| Function | Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities. |
| Protein Name | RegucalcinRcGluconolactonaseGnlSenescence Marker Protein 30Smp-30 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Regucalcin antibodyAnti-Rc antibodyAnti-Gluconolactonase antibodyAnti-Gnl antibodyAnti-Senescence Marker Protein 30 antibodyAnti-Smp-30 antibodyAnti-RGN antibodyAnti-SMP30 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and NHEJ1 knockout (KO) HeLa cells, using [KO Validated] NHEJ1 Rabbit polyclonal antibody (STJ11103937) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 60s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/176582/367429/STJ11103937_1__73085.1713132967.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and NHEJ1 knockout (KO) HeLa cells, using [KO Validated] NHEJ1 Rabbit polyclonal antibody (STJ11103937) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 60s.")
