| Tissue Specificity | Detected in brain, heart and liver (at protein level). Highly expressed in liver, skeletal muscle, kidney and pancreas. Detected at lower levels in heart, brain and placenta. Detected in aorta endothelial cells. Overexpressed in colon, breast, prostate, bladder, lung, and ovarian cancer tissues. |
| Function | Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition. Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation. |
| Protein Name | Regulator Of Cell Cycle RgccResponse Gene To Complement 32 ProteinRgc-32 |
| Database Links | Reactome: R-HSA-6804115 |
| Cellular Localisation | CytoplasmNucleusCytoskeletonMicrotubule Organizing CenterCentrosomeCytoplasmic In Unstimulated CellsNuclear After Activation By ComplementAssociated With The Centrosome During Prometaphase And Metaphase |
| Alternative Antibody Names | Anti-Regulator Of Cell Cycle Rgcc antibodyAnti-Response Gene To Complement 32 Protein antibodyAnti-Rgc-32 antibodyAnti-RGCC antibodyAnti-C13orf15 antibodyAnti-RGC32 antibody |
Information sourced from Uniprot.org
