| Host: | Rabbit |
| Applications: | IF/ICC/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RFX5 |
| Gene ID: | 5993 |
| Uniprot ID: | RFX5_HUMAN |
| Immunogen Region: | 367-616 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 367-616 of human RFX5 (NP_000440.1). |
| Immunogen Sequence: | LSSRAGAPPAAVPIINMILP TVPALPGPGPGPGRAPPGGL TQPRGTENREVGIGGDQGPH DKGVKRTAEVPVSEASGQAP PAKAAKQDIEDTASDAKRKR GRPRKKSGGSGERNSTPLKS AAAMESAQSSRLPWETWGSG GEGNSAGGAERPGPMGEAEK GAVLAQGQGDGTVSKGGRGP GSQHTKEAEDKIPLVPSKVS VIKGSRSQKEAFPLAKGEVD TAPQGNKDLKEHVLQSSLS |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Phosphorylated. |
| Function | Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters. |
| Protein Name | Dna-Binding Protein Rfx5Regulatory Factor X 5 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna-Binding Protein Rfx5 antibodyAnti-Regulatory Factor X 5 antibodyAnti-RFX5 antibody |
Information sourced from Uniprot.org