| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RERE |
| Gene ID: | 473 |
| Uniprot ID: | RERE_HUMAN |
| Immunogen Region: | 1-220 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human RERE (NP_036234.3). |
| Immunogen Sequence: | MTADKDKDKDKEKDRDRDRD REREKRDKARESENSRPRRS CTLEGGAKNYAESDHSEDED NDNNSATAEESTKKNKKKPP KKKSRYERTDTGEITSYITE DDVVYRPGDCVYIESRRPNT PYFICSIQDFKLVHNSQACC RSPTPALCDPPACSLPVASQ PPQHLSEAGRGPVGSKRDHL LMNVKWYYRQSEVPDSVYQH LVQDRHNENDSGRELVITDP |
| Tissue Specificity | Widely expressed. Expressed in tumor cell lines. |
| Function | Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death. |
| Protein Name | Arginine-Glutamic Acid Dipeptide Repeats ProteinAtrophin-1-Like ProteinAtrophin-1-Related Protein |
| Cellular Localisation | NucleusLocalized In Nuclear Bodies Of Variables SizeColocalized With Pml And Bax In Nuclear Pods |
| Alternative Antibody Names | Anti-Arginine-Glutamic Acid Dipeptide Repeats Protein antibodyAnti-Atrophin-1-Like Protein antibodyAnti-Atrophin-1-Related Protein antibodyAnti-RERE antibodyAnti-ARG antibodyAnti-ARP antibodyAnti-ATN1L antibodyAnti-KIAA0458 antibody |
Information sourced from Uniprot.org
