| Tissue Specificity | Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells. |
| Function | Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium. |
| Protein Name | Regenerating Islet-Derived Protein 4Reg-4Gastrointestinal Secretory ProteinReg-Like ProteinRegenerating Islet-Derived Protein IvReg Iv |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Regenerating Islet-Derived Protein 4 antibodyAnti-Reg-4 antibodyAnti-Gastrointestinal Secretory Protein antibodyAnti-Reg-Like Protein antibodyAnti-Regenerating Islet-Derived Protein Iv antibodyAnti-Reg Iv antibodyAnti-REG4 antibodyAnti-GISP antibodyAnti-RELP antibody |
Information sourced from Uniprot.org
