| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-REG4 (23-158) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
REG4 |
| Gene ID: |
83998 |
| Uniprot ID: |
REG4_HUMAN |
| Immunogen Region: |
23-158 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 23-158 of human REG4 (NP_114433.1). |
| Immunogen Sequence: |
DIIMRPSCAPGWFYHKSNCY GYFRKLRNWSDAELECQSYG NGAHLASILSLKEASTIAEY ISGYQRSQPIWIGLHDPQKR QQWQWIDGAMYLYRSWSGKS MGGNKHCAEMSSNNNFLTWS SNECNKRQHFLCKYRP |
| Tissue Specificity | Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells. |
| Function | Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium. |
| Protein Name | Regenerating Islet-Derived Protein 4Reg-4Gastrointestinal Secretory ProteinReg-Like ProteinRegenerating Islet-Derived Protein IvReg Iv |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Regenerating Islet-Derived Protein 4 antibodyAnti-Reg-4 antibodyAnti-Gastrointestinal Secretory Protein antibodyAnti-Reg-Like Protein antibodyAnti-Regenerating Islet-Derived Protein Iv antibodyAnti-Reg Iv antibodyAnti-REG4 antibodyAnti-GISP antibodyAnti-RELP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
