| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RECQL4 |
| Gene ID: | 9401 |
| Uniprot ID: | RECQ4_HUMAN |
| Immunogen Region: | 231-330 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 231-330 of human RECQL4 (NP_004251.3). |
| Immunogen Sequence: | GAGSQGPEASAFQEVSIRVG SPQPSSSGGEKRRWNEEPWE SPAQVQQESSQAGPPSEGAG AVAVEEDPPGEPVQAQPPQP CSSPSNPRYHGLSPSSQARA |
| Tissue Specificity | Ubiquitously expressed, with highest levels in thymus and testis. |
| Function | An ATP-dependent DNA helicase which unwinds dsDNA with a 3'-overhang in a 3'-5' direction. Does not unwind more than 18 bp of dsDNA. May modulate chromosome segregation. The N-terminal domain (residues 1-54) binds DNA Y-shaped DNA better than ss- or dsDNA. The core helicase domain binds ssDNA. |
| Protein Name | Atp-Dependent Dna Helicase Q4Dna 3'-5' Helicase Recq4Dna Helicase - Recq-Like Type 4Recq4RtsRecq Protein-Like 4 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Atp-Dependent Dna Helicase Q4 antibodyAnti-Dna 3'-5' Helicase Recq4 antibodyAnti-Dna Helicase - Recq-Like Type 4 antibodyAnti-Recq4 antibodyAnti-Rts antibodyAnti-Recq Protein-Like 4 antibodyAnti-RECQL4 antibodyAnti-RECQ4 antibody |
Information sourced from Uniprot.org