Anti-Recombinant-TMEM119, OBIF antibody (113-280 Cyt C-Term) [L128/43] (STJA0040534)

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STJA0040534
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Host: Chicken
Applications: ELISA/ICC/IHC/WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Chicken monoclonal anti-Recombinant-TMEM119, OBIF (113-280 Cyt C-Term) for use in ELISA, ICC, IHC and WB in Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : L128/43
Conjugation: Unconjugated
Isotype: IgY
Formulation: 1X PBS, 0.05% Sodium Azide pH 7.4
Purification: Purified by affinity chromatography
Concentration: 1 mg/mL
Storage Instruction: Aliquot and store at ≤-20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Gene Symbol: Tmem119
Gene ID: 231633
Uniprot ID: TM119_MOUSE
Immunogen Region: 113-280 Cyt C-Term
Specificity: No cross-reactivity reported
Immunogen: Fusion protein amino acids 113-280 (cytoplasmic C-terminus) of mouse Tmem119
Immunogen Sequence: Mouse
Tissue Specificity Expressed in spermatocytes and spermatids in the developing testis (at protein level). Expressed in the brain, heart, lung, spleen, skeletal muscle, ovary, testis and epididymis. Predominantly expressed in osteoblasts.
Function Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts. May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Up-regulates the expression of ATF4 which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation.
Protein Name Transmembrane Protein 119
Osteoblast Induction Factor
Obif
Database Links
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cytoplasm
Endoplasmic Reticulum Membrane
Secreted
Alternative Antibody Names Anti-Transmembrane Protein 119 antibody
Anti-Osteoblast Induction Factor antibody
Anti-Obif antibody
Anti-Tmem119 antibody

Information sourced from Uniprot.org

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