Anti-Recombinant-TMEFF2 antibody [RM2K78] (STJA0025943)

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STJA0025943
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Host: Rabbit
Applications: FC/IF/IHC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Tomoregulin-2 is suitable for use in Flow Cytometry, Immunofluorescence, Immunohistochemistry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2K78
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: TMEFF2
Gene ID: 23671
Uniprot ID: TEFF2_HUMAN
Post Translational Modifications O-glycosylated.contains chondroitin sulfate glycosaminoglycans. A soluble form (TMEFF2-ECD) is produced by proteolytic shedding. This shedding can be induced by phorbol ester or pro-inflammatory cytokines such as TNFalpha, and is mediated by ADAM17.
Function May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation.
Protein Name Tomoregulin-2
Tr-2
Hyperplastic Polyposis Protein 1
Transmembrane Protein With Egf-Like And Two Follistatin-Like Domains
Cellular Localisation Isoform 1: Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Membrane
Isoform 3: Secreted
Alternative Antibody Names Anti-Tomoregulin-2 antibody
Anti-Tr-2 antibody
Anti-Hyperplastic Polyposis Protein 1 antibody
Anti-Transmembrane Protein With Egf-Like And Two Follistatin-Like Domains antibody
Anti-TMEFF2 antibody
Anti-HPP1 antibody
Anti-TENB2 antibody
Anti-TPEF antibody
Anti-UNQ178 antibody
Anti-PRO204 antibody

Information sourced from Uniprot.org

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