| Host: | Rabbit |
| Applications: | IHC/IP/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal antibody anti-Recombinant-Spectrin Alpha Chain-Non-Erythrocytic 1 is suitable for use in Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | RM2F06 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide |
| Purification: | Protein A/G purified from cell culture supernatant |
| Dilution Range: | IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000 |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | SPTAN1 |
| Gene ID: | 6709 |
| Uniprot ID: | SPTN1_HUMAN |
| Function | Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. |
| Protein Name | Spectrin Alpha Chain - Non-Erythrocytic 1Alpha-Ii SpectrinFodrin Alpha ChainSpectrin - Non-Erythroid Alpha Subunit |
| Database Links | Reactome: R-HSA-264870Reactome: R-HSA-373753Reactome: R-HSA-375165Reactome: R-HSA-445095Reactome: R-HSA-5673001Reactome: R-HSA-6798695Reactome: R-HSA-6807878Reactome: R-HSA-9013420Reactome: R-HSA-9013424Reactome: R-HSA-9662360Reactome: R-HSA-9662361 |
| Cellular Localisation | CytoplasmCytoskeletonCell CortexExpressed Along The Cell Membrane In Podocytes And Presumptive Tubule Cells During Glomerulogenesis And Is Expressed Along Lateral Cell Margins In Tubule Cells |
| Alternative Antibody Names | Anti-Spectrin Alpha Chain - Non-Erythrocytic 1 antibodyAnti-Alpha-Ii Spectrin antibodyAnti-Fodrin Alpha Chain antibodyAnti-Spectrin - Non-Erythroid Alpha Subunit antibodyAnti-SPTAN1 antibodyAnti-NEAS antibodyAnti-SPTA2 antibody |
Information sourced from Uniprot.org
