Anti-Recombinant-SOX10 antibody [RM1Z52] (STJA0024927)

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STJA0024927
£309.50 - £472.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Transcription Factor Sox-10 is suitable for use in Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM1Z52
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: WB: 1:500-1:1000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: SOX10
Gene ID: 6663
Uniprot ID: SOX10_HUMAN
Function Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3. Transcriptional activator of MBP, via binding to the gene promoter.
Protein Name Transcription Factor Sox-10
Database Links Reactome: R-HSA-9619665
Reactome: R-HSA-9764302
Reactome: R-HSA-9824585
Reactome: R-HSA-9856649
Cellular Localisation Cytoplasm
Nucleus
Mitochondrion Outer Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Alternative Antibody Names Anti-Transcription Factor Sox-10 antibody
Anti-SOX10 antibody

Information sourced from Uniprot.org