Host: | Rabbit |
Applications: | FC/IF/IHC/WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit monoclonal antibody anti-Recombinant-Secreted Frizzled-Related Protein 4 is suitable for use in Flow Cytometry, Immunofluorescence, Immunohistochemistry and Western Blot research applications. |
Clonality : | Monoclonal |
Clone ID : | RM2H85 |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide |
Purification: | Protein A/G purified from cell culture supernatant |
Dilution Range: | FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000 |
Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Gene Symbol: | SFRP4 |
Gene ID: | 6424 |
Uniprot ID: | SFRP4_HUMAN |
Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake. |
Protein Name | Secreted Frizzled-Related Protein 4Sfrp-4Frizzled Protein - Human EndometriumFrphe |
Cellular Localisation | SecretedCytoplasmic In Ovarian Tumor Cells |
Alternative Antibody Names | Anti-Secreted Frizzled-Related Protein 4 antibodyAnti-Sfrp-4 antibodyAnti-Frizzled Protein - Human Endometrium antibodyAnti-Frphe antibodyAnti-SFRP4 antibodyAnti-FRPHE antibody |
Information sourced from Uniprot.org