Function | Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. |
Protein Name | Plasma Protease C1 InhibitorC1 InhC1inhC1 Esterase InhibitorC1-Inhibiting FactorSerpin G1 |
Database Links | Reactome: R-HSA-114608Reactome: R-HSA-140837Reactome: R-HSA-9657689Reactome: R-HSA-977606 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Plasma Protease C1 Inhibitor antibodyAnti-C1 Inh antibodyAnti-C1inh antibodyAnti-C1 Esterase Inhibitor antibodyAnti-C1-Inhibiting Factor antibodyAnti-Serpin G1 antibodyAnti-SERPING1 antibodyAnti-C1IN antibodyAnti-C1NH antibody |
Information sourced from Uniprot.org