Anti-Recombinant-RPS6KB2 antibody [RM2K64] (STJA0025929)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Ribosomal Protein S6 Kinase Beta-2 for use in FC, IF, IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IF/IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2K64 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | RPS6KB2 |
| Gene ID | 6199 |
| Uniprot ID | KS6B2_HUMAN |
Additional Info
| Function | Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7. |
| Protein Name | Ribosomal Protein S6 Kinase Beta-2S6k-Beta-2S6k270 Kda Ribosomal Protein S6 Kinase 2P70s6k2P70-S6k 2S6 Kinase-Related KinaseSrkSerine/Threonine-Protein Kinase 14bP70 Ribosomal S6 Kinase BetaS6k-BetaP70 S6 Kinase BetaP70 S6k-BetaP70 S6kbP70-Beta |
| Database Links | Reactome: R-HSA-198693Reactome: R-HSA-5674400 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Ribosomal Protein S6 Kinase Beta-2 antibodyAnti-S6k-Beta-2 antibodyAnti-S6k2 antibodyAnti-70 Kda Ribosomal Protein S6 Kinase 2 antibodyAnti-P70s6k2 antibodyAnti-P70-S6k 2 antibodyAnti-S6 Kinase-Related Kinase antibodyAnti-Srk antibodyAnti-Serine/Threonine-Protein Kinase 14b antibodyAnti-P70 Ribosomal S6 Kinase Beta antibodyAnti-S6k-Beta antibodyAnti-P70 S6 Kinase Beta antibodyAnti-P70 S6k-Beta antibodyAnti-P70 S6kb antibodyAnti-P70-Beta antibodyAnti-RPS6KB2 antibodyAnti-STK14B antibody |
Information sourced from Uniprot.org