| Host: | Rabbit |
| Applications: | IF/IHC/IP/WB |
| Reactivity: | Human/Mouse/Rat/Pig |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal antibody anti-Recombinant-Phospho-Camp-Dependent Protein Kinase Type Ii-Alpha Regulatory Subunit-S99 is suitable for use in Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | RM1A26 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide |
| Purification: | Protein A/G purified from cell culture supernatant |
| Dilution Range: | IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000 |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | PRKAR2A |
| Gene ID: | 5576 |
| Uniprot ID: | KAP2_HUMAN |
| Post Translational Modifications | Phosphorylated by the activated catalytic chain. |
| Function | Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. |
| Protein Name | Camp-Dependent Protein Kinase Type Ii-Alpha Regulatory Subunit |
| Database Links | Reactome: R-HSA-163615Reactome: R-HSA-164378Reactome: R-HSA-180024Reactome: R-HSA-381676Reactome: R-HSA-432040Reactome: R-HSA-442720Reactome: R-HSA-5610787Reactome: R-HSA-9010642Reactome: R-HSA-9634597Reactome: R-HSA-9660821Reactome: R-HSA-9664323Reactome: R-HSA-983231 |
| Cellular Localisation | CytoplasmCell MembraneColocalizes With Pja2 In The Cytoplasm And The Cell Membrane |
| Alternative Antibody Names | Anti-Camp-Dependent Protein Kinase Type Ii-Alpha Regulatory Subunit antibodyAnti-PRKAR2A antibodyAnti-PKR2 antibodyAnti-PRKAR2 antibody |
Information sourced from Uniprot.org
![Immunofluorescence analysis of L929 cells using [KO Validated] PKA RII Alpha (PRKAR2A) /PKR2 Rabbit polyclonal antibody (STJ25123) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/100335/386658/STJ25123_1__59754.1713155779.jpg?c=1 "Immunofluorescence analysis of L929 cells using [KO Validated] PKA RII Alpha (PRKAR2A) /PKR2 Rabbit polyclonal antibody (STJ25123) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.")
