Host: | Rabbit |
Applications: | IF/IHC/WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit monoclonal antibody anti-Recombinant-Phospho-Histone H14-T17 is suitable for use in Immunofluorescence, Immunohistochemistry and Western Blot research applications. |
Clonality : | Monoclonal |
Clone ID : | RM1C22 |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide |
Purification: | Protein A/G purified from cell culture supernatant |
Dilution Range: | IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000 |
Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Function | Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation. |
Protein Name | Histone H1.4Histone H1bHistone H1s-4 |
Database Links | Reactome: R-HSA-140342Reactome: R-HSA-2559584 |
Cellular Localisation | NucleusChromosomeMainly Localizes In HeterochromatinDysplays A Punctuate Staining Pattern In The Nucleus |
Alternative Antibody Names | Anti-Histone H1.4 antibodyAnti-Histone H1b antibodyAnti-Histone H1s-4 antibodyAnti-H1-4 antibodyAnti-H1F4 antibodyAnti-HIST1H1E antibody |
Information sourced from Uniprot.org