| Host: | Rabbit |
| Applications: | IF/IHC/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Recombinant-Phospho-Histone H14-T17 for use in IF, IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | RM1C22 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Purification: | Protein A/G purified from cell culture supernatant |
| Dilution Range: | IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000 |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Function | Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation. |
| Protein Name | Histone H1.4Histone H1bHistone H1s-4 |
| Database Links | Reactome: R-HSA-140342Reactome: R-HSA-2559584 |
| Cellular Localisation | NucleusChromosomeMainly Localizes In HeterochromatinDysplays A Punctuate Staining Pattern In The Nucleus |
| Alternative Antibody Names | Anti-Histone H1.4 antibodyAnti-Histone H1b antibodyAnti-Histone H1s-4 antibodyAnti-H1-4 antibodyAnti-H1F4 antibodyAnti-HIST1H1E antibody |
Information sourced from Uniprot.org
