Anti-Recombinant-PACSIN3 antibody [RM2S86] (STJA0026644)

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STJA0026644
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Host: Rabbit
Applications: IF/IHC/IP/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Protein Kinase C And Casein Kinase Substrate In Neurons Protein 3 is suitable for use in Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2S86
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IF: 1:50-1:200, IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: PACSIN3
Gene ID: 29763
Uniprot ID: PACN3_HUMAN
Post Translational Modifications Phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC).
Function Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity.
Protein Name Protein Kinase C And Casein Kinase Substrate In Neurons Protein 3
Sh3 Domain-Containing Protein 6511
Database Links Reactome: R-HSA-8856828
Cellular Localisation Cytoplasm
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Detected At The Inner Aspect Of The Plasma Membrane In Myotubes
Alternative Antibody Names Anti-Protein Kinase C And Casein Kinase Substrate In Neurons Protein 3 antibody
Anti-Sh3 Domain-Containing Protein 6511 antibody
Anti-PACSIN3 antibody

Information sourced from Uniprot.org